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A New Approach to PCOS Built Around Insulin

Join 4,000+ women improving their PCOS symptoms—no calorie counting, just science.
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Featured In
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https://www.medscape.com/viewarticle/elusive-pcos-diagnosis-could-explain-obesity-issues-2025a1000ij3
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https://www.glamour.co.za/wellness/healthy-eating/self-test-heres-how-i-benefited-from-drinking-chia-seeds-in-water-everyday-for-a-month-e70581db-b854-48ba-815d-505bd8e5bd9f
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https://wewillcure.com/insights/metabolic-diseases/founder-stories/how-a-pcos-diagnosis-fueled-one-founders-mission-to-disrupt-womens-health
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https://swhr.org/pcos-explored-confronting-and-closing-the-gaps-in-care/
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https://www.coastmonthly.com/features/balancing-act/article_c41abf6e-b6c3-5f0b-9829-7a94ff43a283.html
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https://medium.com/authority-magazine/all?topic=ivf
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How many women are affected

1 in 7

Live with PCOS worldwide

70%

Go undiagnosed

Center
Up to 95%

Are Insulin Resistant

Millions

Managing symptoms daily

A Simple 3-Step Method to Lower Insulin and Finally Feel Better

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Test

Start with our simple at-home test kit to see what your insulin levels are and whether they could be driving your symptoms.

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Track

Monitor your insulin, symptoms, and progress on a Low Insulin Lifestyle to stay on track and see results.

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Transform

Use the app to follow a Low Insulin Lifestyle with education, recipes, and meal plans designed to help lower insulin and improve your symptoms.

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Everything in one app - start free today.

Meal Plans
Simple low insulin meal plans and recipes.
Symptom Tracker
Track mood, weight, and symptoms.
Lab Insights

Upload your labs or connect your Insara Metabolic Kits to track over time.

Education Hub

Simple, science-backed lessons on how insulin may be driving your symptoms and how to lower it.

Recipes

Simple low insulin recipes designed for everyday meals.

Cycle Tracker

Track your cycle and understand patterns over time.

Real results from real women.

  • It’s refreshing to see an evidence-based approach to PCOS care.

    Insulin resistance plays a central role in PCOS, yet it has been overlooked in diagnostic criteria, pre-pregnancy and pregnancy screening, and treatment for far too long. It’s refreshing to see companies finally taking an intentional, evidence-based approach to what should be the foundation of PCOS care.
    Erin Wolff, MD Reproductive
    Endocrinologist

  • My PCOS blood work improved so much that my doctor needed to know what I was doing.

    Dr. Chappell, I hope you don’t mind me sharing this, but my PCOS blood work improved so much with your book that my doctor needed to know what I was doing. I told him about focusing on insulin, and he was so intrigued he took a copy of your book. He said, “Your blood work is finally normal,” and now he’s started checking fasting insulin and C-peptide too. I’m so excited on this journey. Thank you, thank you, thank you!
    Kylie
    @kyliemonacelli

  • My A1C is the lowest it’s ever been, and I feel great.

    Hi! I just want to say thank you for all the educational content you put out there. Although I’m not officially diagnosed with PCOS, I’ve always suspected I’m on the spectrum. As a South Asian female, I’ve dealt with lean PCOS-like symptoms and have a family history of insulin resistance. Your guidance has helped ensure my fasting insulin levels are in a good range, and my A1C is the lowest it’s ever been (5). Most importantly, I feel great. Appreciate all that you do.
    Mytris
    @mytris

  • I had my first positive ovulation test.

    Thank you so much! As a PCOS girlie and a practicing physician assistant, medicine is my world, and your book is truly incredible. The science behind your work and the results are amazing, and yet nobody talks about insulin the way we should with this metabolic dysfunction. I was always told birth control, metformin, etc. I started following a low insulin lifestyle and had my first positive ovulation test. Thank you for all you do for the PCOS community.
    Kylie Monacelli, PA

  • I’ve already lost 12 lbs in just a few weeks.

    "Hey, I just wanted to let you know that I've been following this plan loosely the last 3-4 weeks, having starch as a side only once or twice a week at the most. I've already lost 12 lbs! I haven't been working out nearly as much as I should, but I'm still dropping weight!
    Rissaloo
    @_rissaloo_

  • It’s long overdue that we move beyond one-size-fits-all advice for PCOS.

    PCOS exists along a spectrum, with varying symptoms, and affects women across all body types. The only way we’ll truly improve symptoms and long-term outcomes is by addressing the root cause, and that means making insulin-lowering strategies the foundation of treatment. I’m proud to see Insara working to bring insulin-lowering strategies to the forefront of PCOS care, where they belong.
    Kim Hopkins, PhD, WHNP
  • It Works!! This book is truly a life saver! I struggled with my weight due to pcos for 15 years. I always bounced up and down with weight and could never figure out how to lose consistently or how to keep it off. I have always been consistent in the gym and did clean eating but my weight still wasn’t moving consistently or at all most of the time. Finally I found this amazing book and have followed the low insulin lifestyle and I have dropped 20lbs over the last few months.
    Elise Hassinger (Verified Amazon Purchase)
  • I lost 37 lbs and got pregnant after years of infertility. I started a Low Insulin Lifestyle in December 2024 and in just a few weeks, I lost weight, felt more energized, and started seeing improvements in my cycle. It was incredible how quickly my body responded when I gave it what it needed. I had lost a total of 37 lbs before I became pregnant after several years of struggling with infertility! I am now 20 weeks pregnant and continued to follow this approach and have only gained 6 lbs so far and feel amazing!
    Haylee G
  • To be clear, this is NOT a diet. I absolutely hate diets because I have struggled with my weight literally since I was 8 years old, I have tried every diet, pill, workout plan, and even bariatric surgery that ended up making me ill and in pain even now years later. The science behind insulin, how our bodies use it, and what affects it was fascinating. There was also some info in there that shocked me. I'm recommending this to my friends with PCOS and who have always struggled with their weight and felt miserable. I can't wait to see if this is the answer to our struggles!
    Crystal A. (Verified Amazon Purchase)
  • Addressing insulin resistance early can change the trajectory of women’s health Addressing insulin resistance early, particularly in women of reproductive age, is key to preventing obesity and its associated long-term complications. Efforts to close this gap in care have the potential to change the trajectory of women’s health for generations to come.
    Steven J. Fleischman, MD, MBA, FACOG
    Associate Chief, Department of ObGyn, Yale New Haven Hospital

  • My cycle went from 50–60 days to 33 days.

    Hi Dr. Chappell, I just want to say thank you. I’m so glad I found your book and your profile. I’ve had PCOS my whole life and was always told to just take the pill until I wanted kids. After developing gestational diabetes with my last pregnancy, I started looking into insulin and PCOS, which led me to you. I’ve been following a low insulin lifestyle for three months now, and it’s been amazing. My cycle went from 50–60 days to 33 days.
    @halynahoy

  • We need to address insulin resistance to truly support patients with PCOS.

    As a dermatologist, I often see patients with PCOS struggling with acne, hair thinning, and excess facial hair. While we can treat the symptoms, I’m always looking for resources that address the underlying problem, insulin resistance, so we can support patients from the inside out.
    Janice Wilson
    MD Dermatologist

  • My fasting insulin went from 15 to 6.8 in two months.

    Hi Dr. Chappell! I have some great news to share. My fasting insulin went from 15 to 6.8 after about two months of following a low insulin lifestyle. My A1C is now 5. Thank you so much for sharing your work. It’s truly life-giving.
    G. Rodriguez
    Oct 24, 2023

  • I haven’t felt this good in years.

    Three days of implementing this and I haven’t felt this good in years (I’ve even dropped 2 pounds with the same calorie intake). I’ve struggled with PCOS all my life, and I feel like you gave me an instruction manual to manage this condition better than all the doctors and specialists I’ve seen. I’m going to review your book on all the platforms. 5 stars! From one Aggie to another, thanks and gig ’em.
    @sage.a.brooks

  • The best book about healthy eating I’ve ever read.

    This book is brilliant. The best book about healthy eating that I’ve ever read. It addresses what most people in our society are struggling with. I’m thrilled!
    Martina (Verified Amazon Purchase)
  • Great book for any beginner, scientist, PCOS female, diabetic, health nut - or anyone in between. Dr. Chappell had so many great analogies that helped make a complex topic user friendly. Looking forward to sending this book to so many of my friends who struggle with PCOS and hope this gives them empowerment in this diagnosis. As a women who doesn't have PCOS, this is still a phenomenal read and will certainly shift how I practice medicine in the years to come.
    Marilyn Matthew, MD, PhD
  • I’ve lost 30 lbs without counting a single calorie. I have so many positive changes it's hard to remember them all! I have more energy, no more extreme sugar cravings, and I've lost 30 lbs without counting a single calorie. My periods have become regular for the first time in years, and I just feel better overall.
    JD A.
  • There’s a critical gap in how we address insulin resistance and PCOS. As a dietitian and clinical researcher in nutrition, I’ve seen the lack of education around conditions like insulin resistance and PCOS. Given how common they are, we need a more intentional, evidence-based focus on helping patients lower insulin through dietary strategies that work in the real world. Insara is filling that critical gap with tools and education that translate science into action.
    Mallory Boylan, PhD, RD
  • Enlightening and Empowering Editing this review after practicing this lifestyle for 8 weeks now. My acne has cleared up after 25 years, my energy levels have increased, I can think more clearly, and I’ve lost the remaining 5lbs I’ve been struggling to lose. Low Insulin Lifestyle is an incredibly enlightening and empowering book that has transformed my approach to health and well-being.
    N. Sonbolian, PharmD
  • This book has so much vital information I wish I knew sooner. It's written in a way that speaks to my struggles and has helped me take the blame off my shoulders. I'm changing my lifestyle, hoping to get off metformin. Down almost 5 pounds in the first 2 weeks after years of being stuck.and discouraged. I hope this is a lifestyle change I can implement with my family.
    Life Changing
Frame

4000+ users enjoy Insara

4000+ users enjoy Insara

Real results from real women.

  • We need to address insulin resistance to truly support patients with PCOS.

    As a dermatologist, I often see patients with PCOS struggling with acne, hair thinning, and excess facial hair. While we can treat the symptoms, I’m always looking for resources that address the underlying problem, insulin resistance, so we can support patients from the inside out.
    Janice Wilson
    MD Dermatologist

  • My fasting insulin went from 15 to 6.8 in two months.

    Hi Dr. Chappell! I have some great news to share. My fasting insulin went from 15 to 6.8 after about two months of following a low insulin lifestyle. My A1C is now 5. Thank you so much for sharing your work. It’s truly life-giving.
    G. Rodriguez
    Oct 24, 2023

  • I haven’t felt this good in years.

    Three days of implementing this and I haven’t felt this good in years (I’ve even dropped 2 pounds with the same calorie intake). I’ve struggled with PCOS all my life, and I feel like you gave me an instruction manual to manage this condition better than all the doctors and specialists I’ve seen. I’m going to review your book on all the platforms. 5 stars! From one Aggie to another, thanks and gig ’em.
    @sage.a.brooks

  • The best book about healthy eating I’ve ever read.

    This book is brilliant. The best book about healthy eating that I’ve ever read. It addresses what most people in our society are struggling with. I’m thrilled!
    Martina (Verified Amazon Purchase)
  • Great book for any beginner, scientist, PCOS female, diabetic, health nut - or anyone in between. Dr. Chappell had so many great analogies that helped make a complex topic user friendly. Looking forward to sending this book to so many of my friends who struggle with PCOS and hope this gives them empowerment in this diagnosis. As a women who doesn't have PCOS, this is still a phenomenal read and will certainly shift how I practice medicine in the years to come.
    Marilyn Matthew, MD, PhD
  • I’ve lost 30 lbs without counting a single calorie. I have so many positive changes it's hard to remember them all! I have more energy, no more extreme sugar cravings, and I've lost 30 lbs without counting a single calorie. My periods have become regular for the first time in years, and I just feel better overall.
    JD A.
  • There’s a critical gap in how we address insulin resistance and PCOS. As a dietitian and clinical researcher in nutrition, I’ve seen the lack of education around conditions like insulin resistance and PCOS. Given how common they are, we need a more intentional, evidence-based focus on helping patients lower insulin through dietary strategies that work in the real world. Insara is filling that critical gap with tools and education that translate science into action.
    Mallory Boylan, PhD, RD
  • Enlightening and Empowering Editing this review after practicing this lifestyle for 8 weeks now. My acne has cleared up after 25 years, my energy levels have increased, I can think more clearly, and I’ve lost the remaining 5lbs I’ve been struggling to lose. Low Insulin Lifestyle is an incredibly enlightening and empowering book that has transformed my approach to health and well-being.
    N. Sonbolian, PharmD
  • This book has so much vital information I wish I knew sooner. It's written in a way that speaks to my struggles and has helped me take the blame off my shoulders. I'm changing my lifestyle, hoping to get off metformin. Down almost 5 pounds in the first 2 weeks after years of being stuck.and discouraged. I hope this is a lifestyle change I can implement with my family.
    Life Changing
Frame

4000+ users enjoy Insara

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Ellipse

Built by PCOS experts, backed by science.

Ali Chappell, PhD, MS, RD

Founder and CEO

I’m Dr. Ali Chappell, a Registered Dietitian with both an MS and a PhD in Nutrition, specializing in Reproductive Endocrinology. After earning my doctorate, I completed a National Institutes of Health (NIH)-funded postdoctoral research fellowship focused on nutrition, insulin resistance, and PCOS.


 
Living with PCOS myself is what led me to this work. I’ve dedicated my career to understanding how a Low Insulin Lifestyle can help women better manage their symptoms and feel more in control of their health.


 
In 2021, I received a grant from the National Science Foundation (NSF) I-Corps Program to launch Insara, turning years of research into practical, evidence-based tools for real life.


 
My goal has always been simple: to make this science easier to understand and actually useful for the women who need it most.
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Johnny Chappell

Co-Founder and COO

I’m Johnny Chappell, and I hold a BS in Industrial Distribution from Texas A&M University. After a decade in the industrial sector, my passion for that field waned as my desire to support my wife’s research grew.


Having witnessed Ali’s struggles with PCOS, I’m thrilled to embark on this journey of launching a company that offers answers and support to those in need. I personally experienced the benefits of a Low Insulin Lifestyle by losing 35 pounds and keeping it off for 10 years and counting, proving that it works for men too!


Although Women’s Health isn’t my background, I feel fortunate to be part of growing the vision of Insara Health, knowing it has the potential to positively impact countless lives. Together, we’re dedicated to making a difference.

Jack Stevens

CTO

Jack has 14 years of experience leading software development for bootstrapped, VC-backed, and Fortune 500 companies. He was formerly the Founder and CTO of Framework, an AI-powered e-commerce marketing platform. He’s excited to bring that experience to Insara and help build a platform that makes a meaningful difference in how women understand and improve their health.

Moeez Anwer

Digital marketer

I’m Moeez Anwer is a digital marketing strategist and growth partner focused on building and scaling impactful brands. With expertise in performance marketing, automation, and digital strategy, he helps businesses create systems that drive real growth.


At Insara, his work goes beyond marketing. He is focused on helping bring its mission to life by ensuring the science and support reach those who need it most. He believes that when strategy and purpose come together, they can create meaningful, lasting change.